NECTIN4 and ovarian carcinoma: Multiple phase I clinical trials (NCT03542799, NCT03932565) have reported the use of TRUCKs for recurrent ovarian cancer (MUC16ecto CAR + IL-12) [156], Nectin4-expressing solid tumors (Nectin4/FAP CAR + IL-7 and CCL19 or IL-12), and metastatic colon cancer (EGFR CAR +IL-12).