TNFRSF12A and ischemic stroke: In the MCAO plus hypoxia mouse model of ischemic stroke, a combination of electrophysiological and phosphorylated proteomic approaches revealed that TWEAK acutely inhibits basal synaptic transmission and plasticity through neuronal Fn14 and affects the phosphorylation of pre‐ and postsynaptic proteins in hippocampal brain slices from adult mice.