These cells have been shown to preferentially accumulate at tumor sites, differentiate into proinflammatory M1-like F4/80+ macrophages as well as CD11b-F4/80-CD11c+ conventional dendritic cells (cDC), and amount anti-tumor activity through recruiting and activating tumor specific T cells and/or NK cells (29, 30). Here, ITGAM is linked to neoplasm.