The AUC values were ranked from high to low as follows: Tumor and Total area PD-L1+ (AUC= 0.881), Tumor area CD3+PD-L1+ (AUC= 0.833), Tumor area CD3+ (AUC= 0.826), Tumor area CD4+PD-1+ (AUC= 0.812), Total area CD4+LAG-3+ (AUC= 0.798), Total area CD8+LAG-3+ (AUC= 0.791), Total area CD3+PD-L1+ (AUC= 0.791), Total area LAG-3+ (AUC= 0.777), Tumor area CD8+PD-1 (AUC= 0.729). This evidence concerns the gene LAG3 and neoplasm.