However, there were positive relationships between the numbers of IL-13-producing ILC2 and GATA3+Th2 cells in grades 3 and 4 LTP-AP and their sIgE serum levels, being significant for sIgE-Pru p 3 vs. GATA3+Th2 in the presence of Pru p 3 and CK+Pru p 3 (Figure 5C). This evidence concerns the gene GATA3 and alkaline phosphatase measurement.