For example, cysteine proteases have shown the ability to mediate programmed cell death of lung and blood cancers (Broker et al., 2004; Sukhai et al., 2013) and to promote the maturation of antigen-presenting cells, antigen processing, and presentation to T cells (Olson and Joyce, 2015). The gene discussed is CTSB; the disease is hematopoietic and lymphoid system neoplasm.