In addition to PVT1 mentioned above, lncRNA histocompatibility leukocyte antigen complex P5 (HCP5) can act as ceRNA to inhibit the expression of miR-214-3p and target heparin binding growth factor (HDGF) to regulate the proliferation, invasion, migration, apoptosis and autophagy of PC cells, thus promoting gemcitabine resistance 237. This evidence concerns the gene HDGF and pachyonychia congenita.