MTUS1 and head and neck squamous cell carcinoma: To further examine the in vivo antitumor efficacy by targeting MTUS1/ATIP1, HNSCC PDX models were treated with the MTUS1/ATIP1-overexpressed lentivirus (Lv-OE-ATIP1) or empty lentivirus (Lv-Ctrl) by intratumoral multiple-point injection (Figure 8A).