Another study found that transmembrane and ubiquitin-like domain-containing protein 1 (TMUB1) is a regulator of PTM of PD-L1 in tumor cells that enhances the N-glycosylation and stability of PD-L1 by recruiting STT3A, thereby promoting PD-L1 maturation and tumor immune escape 46. The gene discussed is CD274; the disease is neoplasm.