CD274 and triple-negative breast carcinoma: Epidermal growth factor not only stabilizes PD-L1 by inhibiting GSK3β-β-TrCP-mediated degradation but also promotes the N-glycosylation of PD-L1 at N192 and N200 sites in triple-negative breast cancer (TNBC) cells by upregulating glycosyltransferase B3GNT3, thus promoting the binding of PD-L1 and PD-1 and leading to T cell failure 41.