In B-cell non-Hodgkin lymphoma (B-NHL), glycosyltransferase 1 domain-containing 1 (GLT1D1) enhances the stability of PD-L1 through N-glycosylation, thereby promoting immunosuppression and tumor growth, and is a potential target for B-NHL treatment 44. The gene discussed is GLT1D1; the disease is B-cell non-Hodgkin lymphoma.