Increased RIPK1 and Drp1 expression rather than RIPK3 expression was found in the gastric mucosal samples of mice with PVL and PHG patients compared with that in the corresponding control groups, and the upregulation of RIPK1 and Drp1 in mice with PVL was reversed by IFX treatment (Figure 3A, 3B). This evidence concerns the gene RIPK1 and periventricular leukomalacia.