As a mitochondrion-targeted antioxidant, the ROS scavenger Mito-TEMPO (MT) was demonstrated to relieve gastric mucosal injury and reduce ASC and NLRP3 levels in mice with PVL, and MT could also restore epithelial cell viability in mice with PVL (Figure 8K, Figure S7A, S7B). Here, NLRP3 is linked to periventricular leukomalacia.