Annexin-V based flow cytometry assay demonstrated that the treatment with CILK1-C30 or CILK1-C28 alone significantly induced apoptosis in MDA-MB-231 and BT-549 cells, the combination of CILK1-C30/28 with paclitaxel produced more greater toxicity in tumor cells (Fig. S6D). This evidence concerns the gene CILK1 and neoplasm.