Integrating ALDH2 expression with our previous TNFRSF18/Treg infiltration findings revealed a significant negative correlation between these two factors in TCGA-LIHC (TNFRSF18: R = -0.26, p = 1.6×10-9) and ZS-HCC (R = -0.30, p < 0.0001) cohorts (Figure 5B). This evidence concerns the gene TNFRSF18 and hepatocellular carcinoma.