TGFBR1 and hydrops fetalis: However, inhibition of miR-181c-5p normalized Tgfbr1 expression in the HF + INH group (HF + INH 0.97 ± 0.29, p = 0.04 vs. HF), which confirms that Tgfbr1 is a direct/indirect target of miR-181c-5p in the heart.