SMAD7 and hydrops fetalis: Smad7 mRNA was increased in the HF group (Ctrl 0.46 ± 0.37, HF 1.64 ± 1.04, p = 0.03), and numerically lowered in HF + INH, but without significant effect of inhibitor treatment (HF + INH 0.89 ± 0.97, p = 0.24 vs HF).