Specifically, elevated levels of TGFBI (OR = 1.01; 95% CI, 1.01–1.02; p = 3.26E-05) and PAM (OR = 1.01; 95% CI, 1.01–1.02; p = 6.32E-07) were found to increase the risk of insomnia. This evidence concerns the gene TGFBI and insomnia.