Our analysis pinpointed OGG1 VUSes in two individuals: case LS-298 was compound heterozygous for two OGG1 missense variants, p.Ala330Val and p.Asn331Ser, and case F1001 with several primary carcinomas and adenomas was heterozygous for the OGG1 missense variant p.Leu259Phe. Here, OGG1 is linked to adenoma.