Furthermore, circulating CRP has been suggested to be more related to body composition than type 2 diabetes pathophysiology, since some studies failed to show an association between elevated CRP and type 2 diabetes severity when adjusting for adipose tissue mass (Deacon and Ebringer, 1976; Lee et al., 2009), which limits its sensitivity as a biomarker for monitoring chronic inflammation (Burmeister et al., 2014). The gene discussed is CRP; the disease is type 2 diabetes mellitus.