With the widespread use of next‐generation sequencing techniques, several KCNC1 pathogenic variants were identified in patients with infantile‐onset developmental and epileptic encephalopathy (DEE), developmental encephalopathy without seizures, non‐progressive myoclonus without intellectual disability, and variants of MEAK with radiologic abnormalities of the brain cortex on the MRI (Cameron et al., 2019). Here, KCNC1 is linked to developmental and epileptic encephalopathy.