As Rab10 can be phosphorylated at Thr73 by LRRK2, the phosphorylation of Rab10 was detected, which was lower in the Lrrk2−/−-HE mice than in the WT-HE or Lrrk2G2019S-HE mice (Fig. 7A and Supplementary Fig. 4). The gene discussed is LRRK2; the disease is hereditary elliptocytosis.