GO results show that the target genes were mainly enriched in chromatin and transcriptional initiation (Fig. 3b), while KEGG results reveal that miR-486-3p may be mainly involved in cancer pathways and PI3K/AKT signaling pathway (Fig. 3c), suggesting that miR-486-3p may have epigenetic regulatory potential in tumor progression. The gene discussed is AKT1; the disease is cancer.