TCF12 and glioblastoma: Transfection of TCF12-WT-expressing U251 cells with miR-486-3p reduced the luciferase activity in comparison with TCF12-MUT-expressing U251 cells (Fig. 3h, i), confirming binding between miR-486-3p and TCF12. In addition, we evaluated TCGA data (GBM clinical samples, n = 145), and correlation analysis showed that LINC00606 and TCF12 expression levels were positively correlated (Fig. 3j).