Program P2 (with undefined association to killing, Fig. 2A) was significantly enriched in FAB subtypes M5 (q < 0.05) and M6 (acute erythroid leukemia) and WHO subtypes AML with KMT2A, and NUP98 rearrangement, which has a poor prognosis [32]. This evidence concerns the gene NUP98 and acute myeloid leukemia.