CHCHD10 and cardiomyopathy: In humans, mutations in CHCHD10 cause mitochondrial myopathy, including cardiomyopathy, in addition to Amyotrophic Lateral Sclerosis and other motor neuron disorders (Bannwarth et al, 2014; Ajroud-Driss et al, 2015; Shammas et al, 2022).