According to Kaplan Meier analysis, setting the median expression of DBF4 as a threshold, our study found that high levels of DBF4 expression are associated with adverse survival outcomes in several cancers, including LIHC, ACC, KIRC, KIRP, LGG, etc. (Figs. S2A, S2B, S3A, S3B). This evidence concerns the gene DBF4 and cancer.