Compared to the vehicle group, ZGGS15 low-dose (1.5 mg/kg), high-dose (5 mg/kg), anti-PD-1 antibody (1 mg/kg), ZGGS15 low-dose plus anti-PD-1 antibody (1.5 mg/kg + 1 mg/kg), and ZGGS15 high-dose plus anti-PD-1 antibody (5 mg/kg + 1 mg/kg) could significantly inhibit tumor growth (p < 0.001). Here, PDCD1 is linked to neoplasm.