The anti-TIGIT antibody, anti-LAG-3 antibody, and anti-PD-1 antibody treatment groups could only slightly inhibit tumor growth, with mean tumor volumes of 446.66 ± 25.72 mm3 (TGI = 24.38%), 357.18 ± 63.73 mm3 (TGI = 44.40%), 374.64 ± 66.09 mm3 (TGI = 40.23%) respectively. This evidence concerns the gene PDCD1 and neoplasm.