Compared with the Control group, the mRNA expression of Srebf2, Scap, Hmgcr, Soat1, Npc1, Snai3, Twist1, Itgav, Vegfc, and Tgfbr1 has higher expression in model group, indicating that there is lipid metabolism disorder in model mice. The gene discussed is NPC1; the disease is Disorder of lipid metabolism.