Compared with the Control group, the mRNA expression of Srebf2, Scap, Hmgcr, Soat1, Npc1, Snai3, Twist1, Itgav, Vegfc, and Tgfbr1 has higher expression in model group, indicating that there is lipid metabolism disorder in model mice. Here, HMGCR is linked to Disorder of lipid metabolism.