To understand whether the clinical status associated with T. gondii infection affected the in vitro production of IFN-γ (the major cytokine responsible for immune protection in toxoplasmosis), we compared the PBMC IFN-γ response with TE, and NP/TE in 21 individuals: six that were uninfected with T. gondii, 11 chronically infected without ocular lesions, and four chronically infected with ocular lesions (Table 1). Here, IFNG is linked to toxoplasmosis.