We found multiple instances of glutamate receptors (e.g., GRM1, 2, 4, 5) and glutamate decarboxylase 1 and 2 (GAD1, 2), with the axes of GAD2 with GRM1, 4 and 5 being always significantly associated with lower survival in endometrium and thyroid cancer tissues. This evidence concerns the gene GRM1 and thyroid gland carcinoma.