CYP19A1 and major depressive disorder: Patients undergoing ET performed worse than controls on verbal and visual learning/memory, executive function, and processing speed, but not on psychomotor efficiency or visuospatial function. Tamoxifen and aromatase inhibitors patients did not differ from one another, although tamoxifen patients performed better than non-steroidal aromatase inhibitors patients. Most studies reported no significant differences in anxiety or depression.