In patient 8 the tumor on the right side was detected 32 months after the tumor on the left side, and the unique somatic mutations present on the right tumor were RYR3 (SNV, c.G7990A, p.E2664K), DDI1 (SNV, c.C107G, p.A36G), FCGRT (stop-gain, c.G155A, p.W52X), SIVA (SNV, c.G478A, p.D160N), SLC28A3 (SNV, c.G202A, p.E68K). This evidence concerns the gene RYR3 and neoplasm.