IFNG and Zika virus infectious disease: In order to address the question of the early involvement of T cells in the early phases of acute ZIKV infection, and to evaluate whether T cells show similar co-expression of phospho-STAT5 and IFN-γ, we investigated in the present study the T cell activation and functional status and the T cell specificities for ZIKV in the same cohort of Brazilian patients [11] in which we had previously conducted our NK cell analysis [16].