GSTM1 and adenoma: The empirical underpinnings of these findings not only support the role of FIT screening for both primary prevention of arresting incident CRC through the removal of adenoma by colonoscopy and the early detection of invasive CRC but also provide the plausible avenue for the formulation of personalized CRC screening using FIT.19,20 As mentioned in previous studies, risk stratification of the underlying population based on f-Hb categories facilitates surveillance of the high-risk group with intensive follow-up and repeated screening of the low-risk group with longer screen intervals.13,16,21,22