PTPRG and esophageal squamous cell carcinoma: In ESCC, researchers reported many lncRNAS have emerged as potent regulators of glycolysis, such as lncRNA G077640 [34], lncRNA-LET [35], lncRNA PTPRG-AS1 [34], et al. Concerning the correlation between RMRP and glycolysis, a report has illustrated that RMRP deficiency contributes to the reduction of glucose uptake, lactic acid, and ATP production in ovarian cancer cells resistant to paclitaxel [16].