ARHGEF38 and metastatic malignant neoplasm in the lymph nodes: 2019; Sun 2021). Liu et al. observed that ARHGEF38 protein in lymph node metastasis patients was significantly higher than that in the non-metastatic patients, which may suggest that the high expression of ARHGEF38 is more prone to distant metastasis (Liu et al. Jun. 2019). Our study reveals for the first time that ARHGEF38 may be used as potential indicator of poor prognosis in TNBC patients.