As for the immunologic index, the positivity for different autoantibodies in pSS-ILD groups was as follows: 87 cases (85.29%) for ANA, 65 cases (63.73%) for Ro52, 65 cases (63.73%) for Ro60, 39 cases (38.24%) for SSB, and 9 cases (8.82%) for anti-centromere antibodies. The gene discussed is TRIM21; the disease is interstitial lung disease.