These data suggest a significant impact on vaccine recipients, including the large number of mRNA-LNPs that are injected, their rapid and widespread distribution particularly into specific organs, the amount of S-protein produced, its long persistence in the body, and increased susceptibility to infection. Next, we consider each factor that may contribute to the involvement of the mRNA-LNP SARS-CoV-2 vaccine in increasing mortality from all cancers and some specific cancer types. This evidence concerns the gene PROS1 and cancer.