Furthermore, the upregulation of activating transcription factor 4 (ATF4) by YTHDF2 results in an increase in the transcript levels of DNA damage‐inducible transcript 4 (DDIT4), an mTOR inhibitor, thereby facilitating prosurvival autophagy during glutaminolysis inhibition in CRC.400. The gene discussed is ATF4; the disease is colorectal carcinoma.