Moreover, high levels of inflammatory/arthrogenic factors, including cytokines (TNF-α, IL-6, IL-7, IL-15, and BAFF) and chemokines (CCL-2, CCL-5, and CXCL-10) have been reported in the serum and/or synovia of rheumatoid arthritis patients (88–90). The gene discussed is CCL2; the disease is rheumatoid arthritis.