After stringent quality control, we isolated 2968 fibroblasts and identified two primary fibroblast classes through unsupervised clustering: tumor-associated fibroblasts (CAF_C1_CLU, CAF_C2_MME) and tumor-associated myofibroblasts (myCAF_C1_MYH11, myCAF_C2_PDGFA) (Figure 7A). This evidence concerns the gene MYH11 and neoplasm.