AKT1 and cancer: GSVA pathway enrichment analysis demonstrated that GC B cells primarily enriched in pathways associated with cell proliferation and growth, plasma cells in angiogenesis and cancer cell proliferation, and memory B cells in WNT beta catenin signaling, PI3k AKT mtor signaling, and DNA repair pathways, reflecting their distinct roles in immune regulation, antigen response, and collaboration with other immune cells.