EGFR and non-small cell lung carcinoma: It is important to note that Nci-H1650 and Nci-H1975 harbor EGFR mutations, among others, (Nci-H1650 additionally has TP53 mutations and is PTEN null), whereas Nci-H522, in comparison to the other analyzed NSCLC cell lines, “only” contains a TP53 mutation (in codon 191).