IGFBP1 and Behcet disease: However, the plasma levels of IGF-2 (U = 227, p-value = 0.478), IGFBP-1 (t (38) = 0.53, p-value = 0.597), and IGFBP-7 (U = 252, p-value = 0.165) remained non-significant between BD patients and C (Figures 1A, B, E, respectively; Table 1).