Alzheimer’s disease is a neurodegenerative brain disease that is mainly characterized by memory loss, cognitive decline, and pathological signs of extracellular neuritic plaques that are composed of amyloid-β (Aβ) protein and intracellular neurofibrillary tangles that contain phosphorylated Tau protein (Scheltens et al., 2016). Here, MAPT is linked to Alzheimer disease.