GSEA analysis shows (Figure 1C–K) that the DEGs in the OA merged dataset mainly participate in the Allograft rejection, Apoptosis, Insulin signaling pathway, JAK STAT signaling pathway, Lysosome, MAPK signaling pathway, Oxidative phonology, Parkinsons disease, and T cell receiver signaling pathway. This evidence concerns the gene SOAT1 and Parkinson disease.