GEPIA2 exhibited that ZNF536 was predominantly expressed in glioma and pheochromocytoma and paraganglioma, and the two main isoforms (ENST00000355537.3 and ENST00000592773.2) showed a similar expression pattern (Additional file 4: Figure S3A). Here, ZNF536 is linked to hereditary pheochromocytoma-paraganglioma.