Currently, routine laboratory parameters for coagulation testing, such as D-dimer, FDP, prothrombin Time, activated partial thromboplastin time, thrombin time, fibrinogen and antithrombin III, etc. However, these parameters are passively detected after late thrombosis and are used to detect and screen for thrombosis in the later stage. Here, SERPINC1 is linked to Venous thrombosis.