Under normoxia, we found that infection with Fnn modulated the expression of the following genes: CBX7, LINC010189, SEMA6B, MYO1C, CARD8, ELN, and TMOD3. In hypoxia, these include WDYHV1, TSPAN19, INFGR2, CLUAP1, and SND1. These genes have been previously found to adversely impact CRC progression. The gene discussed is SEMA6B; the disease is colorectal carcinoma.