Furthermore, in BRCA, CHOL, CLL, CRC (COADREAD), GBM, HNSC, KIRC, LIHC, MCC, NHL, NSCLC, PAAD, SCC, SKCM, UCEC, and UVM, both CD47 and TNFRSF9 were co-expressed on CD8 + exhausted T cells. The gene discussed is CD8A; the disease is B-cell chronic lymphocytic leukemia.