Analysis of the TCGA database revealed a notable increase in cytotoxic CD8 + T cell infiltration in BLCA, BRCA, CESC, COAD, COADREAD, ESAD, ESCA, GBM, HNSC, KIRC, LUSC, OV, SKCM, STAD, TGCT, THCA, and UCS when comparing the CD47 high and low expression groups. The gene discussed is CD8A; the disease is bladder transitional cell carcinoma.