Noteworthy findings included TNFRSF9 ranking among the top three co-expressed genes in BRCA, COAD, ESCA, ESAD, ESCC, GBM, LUSC, OV, and DLBC (with correlation coefficients exceeding 0.5 but not ranking first), and CD274 ranking among the top three in BLCA, BRCA, CESC, COAD, READ, CRC, LAML, LGG, LUAD, OSCC, PCPG, PRAD, READ, SARC, SKCM, STAD, and THCA. The gene discussed is CD274; the disease is esophageal squamous cell carcinoma.