Specifically, our analysis revealed that CD47 was prominently expressed on CD8 + exhausted T cells (CD8 + Tex), exhibiting significantly higher expression levels compared to other CD8 + T cell subsets in AML, BRCA, CHOL, CLL, CRC, ESCA, Glioma, HNSC, KICH, LIHC, MCC, MM, NHL, NSCLC, OS, OV, PRAD, SCC, SCLC, SKCM, THCA, and UVM (Fig. 6c). Here, CD8A is linked to acute myeloid leukemia.