Using RNA sequencing data obtained from OncoDB, ANGPT-2 (AUC = 90.8%) and VEGF-A (AUC = 95.1%) in COAD and VEGF-A in READ (AUC = 97.3%) had AUC > 90% and can be diagnostic factors for colorectal cancer (Supplementary File 1). This evidence concerns the gene ANGPT2 and colorectal cancer.