As the result of MaxQuant analysis, 280 proteins were upregulated and 203 were downregulated in sEVs from IFN-γ-treated tumour cells, while 263 proteins were upregulated and 105 were downregulated in sEVs from tumour cells treated with aT-sEVs (Supplementary Fig. 6b). This evidence concerns the gene IFNG and neoplasm.