Further analysis of a T-lymphocyte-specific scRNA-seq study of blood isolated from eight PD patients and six healthy controls revealed that PATL2 is significantly enriched in terminal effector CD8+ and cytotoxic CD4 + T-lymphocytes (Supplementary Fig. 5B) whose populations were both found to be significantly expanded in PD42. This evidence concerns the gene PATL2 and Parkinson disease.