The majority of tumors (including patients with the provisional pedHGG_A/B subclass) were classified as diffuse pedHGG, H3-wt, and IDH-wt (pedHGG_H3-/IDH-wt) (n = 32/52, 61.5%), followed by astrocytoma, IDH1-mutant (n = 5, 9.6%), and diffuse hemispheric glioma, H3 G34-mutant (n = 3, 5.8%). Here, IDH1 is linked to astrocytoma (excluding glioblastoma).