In this case, NEAT1, which is upregulated by infection, associates with HEXIM1, DNA-PK, and paraspeckle proteins (SFPQ, NONO, PSPC1, RBM14, and MATRIN3) to form a complex named HEXIM1-DNA-PK-paraspeckle components ribonucleoprotein(HDP-RNP) [64]. The gene discussed is HEXIM1; the disease is infection.